Create a Solver class object using the Random Forest solver

Create a Solver class object using the Random Forest solver

RandomForestSolver(
  mtx.assay = matrix(),
  targetGene,
  candidateRegulators,
  regulatorWeights = rep(1, length(candidateRegulators)),
  quiet = TRUE
)

Arguments

mtx.assay

An assay matrix of gene expression data
targetGene

A designated target gene that should be part of the mtx.assay data
candidateRegulators

The designated set of transcription factors that could be associated with the target gene
regulatorWeights

A set of weights on the transcription factors (default = rep(1, length(candidateRegulators)))
quiet

A logical denoting whether or not the solver should print output

Value

A Solver class object with Random Forest as the solver

See also

solve.RandomForest, getAssayData

Other Solver class objects: BayesSpikeSolver, EnsembleSolver, HumanDHSFilter-class, LassoPVSolver, LassoSolver, PearsonSolver, RidgeSolver, Solver-class, SpearmanSolver, SqrtLassoSolver, XGBoostSolver

Examples

load(system.file(package="trena", "extdata/ampAD.154genes.mef2cTFs.278samples.RData"))
targetGene <- "MEF2C"
candidateRegulators <- setdiff(rownames(mtx.sub), targetGene)
rf.solver <- RandomForestSolver(mtx.sub, targetGene, candidateRegulators)